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Stem Cell Hair Transplant – the future of hair restoration explained

stem cell hair transplant


  • Stem cells are your body’s core cells from which every specialist cell is born. These cells also repair and replace damaged ones that cannot do that independently. Similarly, they hold a potential for the dermatology field as well.
  • A hair transplant that contains stem cells is the process where healthy stem cells are extracted from the donor area to the balding area of the scalp.
  • As this discovery is still relatively new, it is still not entirely clear if they are a one-time solution or should be done regularly. However, the existing studies show they’re a tremendous supporting method for hair transplants.
  • Ultimately, using this method and many other supportive techniques prescribed by a doctor will be your best choice. And even though this method is yet to be FDA-approved, it has to potentially be the next step in hair restoration.
  • UnitedCare uses Regenera Activa to stop hair loss and promote hair growth through stem cell hair transplants.

Did you know that the average person is born with 100,000 hair follicles, and not a single hair follicle is produced on our scalp ever again?

Although the hair grows and falls and then grows again from these follicles, which can be thought of as the factory of hair, when the follicles themselves fall out, they’re never replaced.

And that’s what makes hair loss an issue 50% of men have to go through by the age of 50.

In this blog, I want to talk about what these new discoveries are and how exactly they’ll help us:

Also, I’ll tackle a few misconceptions about the topic.

But let’s start with the basics:

What Is a Stem Cell?

Stem cells can be referred to as your body’s raw materials, the very basic form of animal cells which all the other specialist cells are derived from. In addition to enabling us to understand the wonders of our systems and cells, stem cells are also used to repair and replace cells we can’t replace on our own.

They can, in the future, be used to create and replace any of our organs or tissue, which makes them a significant and exciting discovery in the field of biology and medicine.

Stem Cell Procedure Background

It was 1961 when James Till, a biophysicist, and Ernest McCulloch, a cellular biologist, first discovered stem cells at Ontario Cancer Institute, Canada.

Although their research didn’t echo at the time because the research was more theoretical than practical at first. Later, as the technology caught up to understand and utilize the potential of stem cells, a sudden influx of attention flowed through the stem cell theory.

When extracted from your bone marrow or blood stream and injected back into damaged tissues, it shows significant improvements in speed and extent of healing.

Today, with a billion-dollar industry revolving around this magnificent discovery, thousands of scientists are trying to take a step toward the future using these stem cells, including experts in dermo-cosmetics and hair restoration.

And how exactly does a stem cell help?

Stem cells extracted from your blood through a centrifuge machine like Rigenera Activa are then injected back into the area that the healing promotion is intended for. After this injection, stem cells start to multiply and reinforce the damaged tissue.

Since stem cells are your own body’s agents, it has minimal side effects, and compared to most regenerative treatments, it yields the best results.

What Is a Stem Cell Hair Transplant

A stem cell hair transplant is a process where scalp tissues are extracted from the donor area using a medical punch device, then stem cells are extracted from this tissue using centrifugation before injecting these stem cells into bald areas of the scalp.

Stem Cell Hair Restoration Background

In a 2017 study, researchers from the University of Rome School of Medicine developed a new method to separate human stem cells from the adipose tissue harvested using a punch biopsy tool.

They conducted an experiment on 11 patients with male pattern baldness in the late stages, aged between 38 and 61.

They injected the patients with the stem cells they harvested from each patient’s donor area. This study was a defining work for stem cell hair therapies since they saw a 29% increase in hair density in a matter of just 28 weeks.

Therefore, the success of stem cell hair transplant is a 29% ±5% increase in hair density.

This study kicked a significant amount of excitement in the field of hair restoration since it can mean that patients can battle hair loss without any serious surgical procedure, with their body’s own resources.

Stem Cell Hair Transplant Process

So, what’s the exact process?

In this section, I’ll dive deeper and look into the process of a stem cell transplant for pattern baldness step by step.

Harvesting Tissue in Stem Cell Transplant

stem cell harvesting hair loss
Harvesting – Steps of the stem cell therapy from the 2017 study.

Initially, the surgeon will need deep tissue from the donor area to extract stem cells. So, using a biopsy punch tool called “Rigenera Securdrill Device”, tissue is extracted from the scalp.

Then, these scalp tissues are cut into strips of 2mm by 2mm to more easily separate stem cells in the next step.

Extracting Stem Cells from Tissue

The cut strips of tissue are then centrifugated at 80 RPM per minute using a centrifuge tool like Rigenera Activa, which is a device that can separate fluids and solids of different densities from each other.

stem cell hair transplant unitedcare
Stem Cell Extraction – Rigenera Activa at our clinic, UnitedCare

60 seconds later, the suspension that is separated from the tissue that contains stem cells is filled into a mechanical injection device.

Injecting Stem Cells into the Scalp

stem cell injection hair loss
Injection – Steps of the stem cell therapy from the 2017 study.

And in the final step, these mechanical injector is used to inject the solution into the patient’s skin, targeting the bald areas of the scalp.

Stem Cell Hair Transplant Healing Period

The punch used in stem cell hair transplantation is much bigger than in regular hair transplants. Therefore it causes a relatively more extensive but small number of wounds that takes a while to heal.

The punch size I use in my FUE operations: 0.8 mm

Stem cell hair transplant punch size: 3 or 4mm

Stem cell hair transplant puch size (3-4mm) vs FUE punch size (0.8mm) comparison
Stem cell hair transplant puch size (3-4mm) vs FUE punch size (0.8mm)

In FUE operation, 3000-4000 holes are opened with FUE punches. However, in stem cell hair transplant, 3 to 5 holes are enough.

Even if a number of holes is low in stem cell operation, Due to relatively big punch wounds, a couple of weeks and a good wound care is a must.

There is no hair shedding, shock loss, or growth phases after a stem cell hair transplant as a regular hair transplant. Other than wounds on the back of the head, there is nothing to be healed.

Therefore, a patient can start daily activities after a week when the wounds crust over, which protects wounds from sweat and dust.

However, a patient should use 50+ sunscreen until the wounds are healed in 4 to 6 weeks after the stem cell hair transplant in order not to have sun spots on punch wounds.

Do Stem Cell Hair Transplants Even Work?

The reason numerous experts refer to stem cell hair transplants as the next step in hair restoration is that it is extremely promising, especially considering the study I’ve just mentioned.

Here is one of the patients who underwent the experimental stem cell therapy, and his results at the beginning of the study, 3 weeks later, 9 weeks, and 23 weeks following the injection, respectively.

stem cell hair loss before and after
Results from the 2017 study on stem cell hair transplants.

As we’ve mentioned in a previous section of this blog, the researchers observed a 29% average increase in hair density 23 weeks after the injection. This increase is much more than every other non-surgical hair restoration method in much less time.

How long does an implanted stem cell last?

Although stem cells have proven that they can act as a solid way to stop hair loss, they might not be a one-off operation.

Just like various other non-surgical treatments that include injections or laser therapies, stem cell injections might be needed to be done on a regular basis to keep your hair healthy and strong.

Or it might not. Once the lack of published research on this subject is clear, we can have a better understanding of the exact steps of the process.

How much a stem cell hair transplant cost worldwide?

The cost of stem cell hair transplant at UnitedCare Clinic Turkey is 1000€ as of 10 July 2023.

Average worldwide costs of stem cell hair transplant as of 2023 is as follows:

Turkey: 1000€ – 3000€

USA: 5000$- 15000$

England: 3000£ – 8000£

India: 1000$ – 2500$

Will Stem Cells Cure Baldness?

Most experts, including myself, agree that the future of medicine and biology, including the treatment of hair loss, is in stem cells.

Unless there is a brand new method that will cure baldness once and for all, stem cell therapies and stem cell hair transplants seem to be the next step in hair restoration.

Today, stem cell injections are scientifically proven to help with slowing down hair loss and promoting hair growth, if you’re in the early stages of your hair loss.

And you can get a top-of-the-line and affordable stem cell treatment at UnitedCare.

However, if your hair loss has progressed, you might the help of additional treatments to restore your natural look:

Definitive Solutions to Balding: DHI and Sapphire FUE

Although stem cells are much more promising, they won’t help you get back to your natural self and appearance by this time next year.

But, FUE and DHI hair transplants enrichened with bio-enhancements will.

At the moment, the most efficient and the most advanced hair restoration methods are two variations of the traditional FUE:

1️⃣ Direct Hair Implantation: DHI, invented by DHI Medical Group in 1999, is a modified variation of FUE where an implanter pen replaces forceps and scalpels used in the implantation stage of hair transplant surgery. This way, the action is reduced to a single motion which allows for better control over the angle and depth of implantation. The recovery time is faster, the scarring is much less, and the end quality is much better.

2️⃣ Sapphire FUE: Sapphire FUE is also a modified version of FUE that also replaces scalpels with a scalpel knife that has a sapphire tip, which makes it much sharper and allows for even smaller incisions. With Sapphire FUE, the recovery and angles of incisions are much better, and the results look even more natural.

🧪 Bio-Enhancements: In traditional FUE and FUT surgeries, the harvested grafts are kept out of the body in proper storage liquid, which can harm the grafts and damage them, lengthening the healing process. With bio-enhancements such as liposomal ATP, HypoThermosol, and ACell, along with PRP injections used throughout the surgery, experts have seen a drastic increase in the recovery periods.

So, even though the future of hair restoration is not here, you can restore your natural hair today with the expert touch and the proper techniques.

Take the First Step with UnitedCare

At UnitedCare, we believe in progress and success.

We believe that medicine is progressing forward and will eventually find a much better and much more efficient way of treating hair loss. So, we adopt clinically proven and regulated strategies to ensure we do our best to help our patients succeed.

As a dermatologist duo with 20 years of combined experience, we’ve adopted a holistic approach to hair loss; stem cell treatments combined with DHI/Sapphire FUE and bio-enhancements and helpful medications to restore your natural hairline.

stem cell hair transplant surgeon
Dermatologist Dr. Utkan K. operating on a hair loss patients

We’re just a click away 👇

Your current best bet for success is here at UnitedCare.

Ensure the success of your hair transplant with STEM CELLS, FUE SURGERIES, and bio enhancements:

Frequently Asked Questions (FAQs)

How much does the stem cell hair transplant cost?

Although the method isn’t yet cleared or approved by the U.S. FDA, you can get a stem cell hair transplant in investigational clinics in other parts of the world with costs ranging between $4000 and $10,000. The cost will change according to what you need, what the clinic charges on a basic level, and of course the country the clinic is located in.

Can stem cells cure baldness?

The potential of stem cells is unlimited, and the thought of stem cells being the complete and absolute cure for baldness makes sense. Currently, injections of stem cells deep into the tissue in bald areas of the patient’s scalp are being tested in various clinics with great promise of success.

Is stem cell the same as PRP?

Platelet Rich Plasma (PRP) and stem cells are two different agents. Although PRP injections promote growth and healing, stem cells can actually regenerate and even replace damaged or destroyed tissue in the target area. Also, stem cells have returned much better results than PRP injections in healing and promoting growth.

Dr. Utkan Kiziltac

Utkan Kızıltaç, MD, WFUE, ISHRS Assc

Chief Physician and Dermatologist Hair Transplant Surgeon of UnitedCare, a dermatology clinic helping patients become the best version of themselves.

9 thoughts on “Stem Cell Hair Transplant – the future of hair restoration explained”

  1. Dear Dr.
    It is a well written article with clear explanations on current state of that new technique.
    Please tell me when that will be approved and with effective result and operational in Turkey.
    I have go many old bad French surgeries FUT (so I distrusted them) followed by much better FUE in Turkey (Istanbul). But now my donor zone is bad and I am 64 yo…So Is there any future hope?
    Also what do you think of micropigmentation?
    I look, forward to hearing from you.


    1. Hello Franck,

      Thank you for your kind words.

      Unfortunately, there is no treatment in the literature showing completely new hair follicle growth out of stem cells. Mesenchymal stem cells can evolve into other cells, but they are not shown to produce new hairs out of nowhere.

      Regenera Stem Cell, or other treatments like G-cell, can’t multiply or create hairs out of stem cells. However, they are proven to increase hair density. (29% density increase in treatment area, 1% in the placebo area in a study.)

      So, the marketed treatments are to stimulate hair growth and regeneration.

      To see what’s are the newest hair transplant methods and what’s possible, you can check out my article.


  2. Hey I just wanted to know if stem cell injection therapy should be done before an FUE procedure and how many days before a hair transplant can you do stem cell injection?

  3. Hello Hamza,

    It can be applied even one day before a hair transplant.

    When stem cell therapy is applied before/after hair transplantation, it has been proven that surgical wounds heal faster, the rate of hair regrowth increases, and the duration of shock hair loss is shortened.


  4. Hi doctor.

    What treatment would you recommended at current time, Stem cell or Fue for density and more natural look?


  5. Hello Dr utkan. Hope you’re doing well.
    Thank you very much for your very informative article. I have only one inquiry.
    I would like to know what is the difference between regenira activa and G-cell therapy? I have searched deeply to know which one is better as i know each one has a different mechanism. As far I Know regenira works in grinding the tissue then inject it while G-cell work on only do cell suspension. The tissue suppose to have more life span in comparison to cells. So please let me know. And whose the best choice to go with.
    Greetings. Ahmed

    1. Hello Ahmed,

      To be honest, there is no comparative scientific study conducted by independent institutions; studies are often biased.

      Based on my own experience and the experiences of my fellows, I can say that there are no visible differences between the results of Regenera Activa and G-cell therapy.


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